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Helen McIlleron Selected Research

Isoniazid (Ftivazide)

1/2022Pharmacogenetics of interaction between depot medroxyprogesterone acetate and efavirenz, rifampicin, and isoniazid during treatment of HIV and tuberculosis.
1/2022Pharmacokinetics of standard versus high-dose isoniazid for treatment of multidrug-resistant tuberculosis.
1/2021Effect of Isoniazid Intake on Ethionamide Pharmacokinetics and Target Attainment in Multidrug-Resistant Tuberculosis Patients.
1/2020Population Pharmacokinetics of Isoniazid, Pyrazinamide, and Ethambutol in Pregnant South African Women with Tuberculosis and HIV.
1/2019A Systematic Review on the Effect of HIV Infection on the Pharmacokinetics of First-Line Tuberculosis Drugs.
1/2019Current research toward optimizing dosing of first-line antituberculosis treatment.
1/2019Effects of genetic variability on rifampicin and isoniazid pharmacokinetics in South African patients with recurrent tuberculosis.
11/2017A Review of Moxifloxacin for the Treatment of Drug-Susceptible Tuberculosis.
5/2017Concentration-Dependent Antagonism and Culture Conversion in Pulmonary Tuberculosis.
1/2017Effects on the QT Interval of a Gatifloxacin-Containing Regimen versus Standard Treatment of Pulmonary Tuberculosis.
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Helen McIlleron Research Topics

Disease

67Tuberculosis (Tuberculoses)
10/2022 - 11/2005
17Multidrug-Resistant Tuberculosis (Drug-Resistant Tuberculosis)
01/2022 - 07/2012
15Pulmonary Tuberculosis
11/2018 - 07/2005
11Body Weight (Weight, Body)
01/2021 - 04/2006
9HIV Infections (HIV Infection)
12/2020 - 06/2009
4Coinfection
05/2022 - 11/2014
4Infections
01/2012 - 04/2006
3Drug-Related Side Effects and Adverse Reactions
10/2016 - 11/2007
3Immune Reconstitution Inflammatory Syndrome
12/2013 - 08/2007
2Neutropenia
02/2015 - 11/2014
1Malnutrition (Nutritional Deficiencies)
01/2022
1Acquired Immunodeficiency Syndrome (AIDS)
01/2022
1Peripheral Nervous System Diseases (PNS Diseases)
04/2021
1Psychotic Disorders (Schizoaffective Disorder)
04/2021
1Sepsis (Septicemia)
01/2020
1Hepatitis
01/2020
1Hearing Loss (Hearing Impairment)
01/2020
1Viremia
12/2016
1Lipodystrophy
02/2016
1Hypersensitivity (Allergy)
02/2016
1Uveitis
11/2014
1Nausea
01/2012
1Diarrhea
01/2012
1Kwashiorkor
06/2009
1Opportunistic Infections (Opportunistic Infection)
08/2007
1Falciparum Malaria (Plasmodium falciparum Malaria)
11/2006
1Malaria
11/2006

Drug/Important Bio-Agent (IBA)

39Pharmaceutical PreparationsIBA
10/2022 - 04/2006
39Rifampin (Rifampicin)FDA LinkGeneric
05/2022 - 07/2005
21Isoniazid (Ftivazide)FDA LinkGeneric
01/2022 - 04/2006
17PyrazinamideFDA LinkGeneric
01/2020 - 04/2006
12Ritonavir (Norvir)FDA Link
05/2022 - 10/2010
12LopinavirFDA Link
05/2022 - 10/2010
11Ethambutol (Myambutol)FDA LinkGeneric
12/2020 - 04/2006
5Gatifloxacin (Zymar)FDA Link
11/2018 - 12/2007
4abacavir (Ziagen)FDA Link
01/2022 - 02/2016
4bedaquiline (R207910)IBA
01/2022 - 01/2014
4Nevirapine (Viramune)FDA Link
12/2016 - 02/2008
3Cycloserine (Seromycin)FDA Link
04/2021 - 11/2018
3Moxifloxacin (Avelox)FDA Link
11/2018 - 11/2017
3lopinavir-ritonavir drug combination (Kaletra)FDA Link
01/2018 - 01/2012
3rifapentine (Priftin)FDA Link
11/2017 - 07/2005
3Rifabutin (Ansamycin)FDA Link
01/2016 - 11/2014
2efavirenz (Sustiva)FDA Link
01/2022 - 01/2015
2Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric
01/2022 - 10/2021
2terizidoneIBA
04/2021 - 10/2020
2Ethionamide (Trecator-SC)FDA Link
01/2021 - 01/2020
2RifamycinsIBA
11/2017 - 06/2015
2Protease Inhibitors (Protease Inhibitor)IBA
06/2015 - 11/2014
1Aminosalicylic Acid (Rezipas)FDA Link
01/2022
1Contraceptive Agents (Contraceptives)IBA
10/2021
1Pyridoxine (Pyridoxin)FDA LinkGeneric
04/2021
1KanamycinFDA Link
01/2020
1Lactic Acid (Lactate)FDA LinkGeneric
01/2020
1Drug CombinationsIBA
01/2019
1pretomanidIBA
11/2017
1QuinolonesIBA
11/2017
1Zidovudine (Retrovir)FDA LinkGeneric
02/2016
1Cytochrome P-450 CYP3AIBA
02/2015
1OPC-67683IBA
01/2014
1Biomarkers (Surrogate Marker)IBA
02/2013
1Lamivudine (Epivir)FDA Link
08/2012
1FluoroquinolonesIBA
07/2012
1Ofloxacin (Ofloxacine)FDA LinkGeneric
07/2012
1EnzymesIBA
04/2012
1Transaminases (Aminotransferases)IBA
01/2012
1Interferon-gamma (Interferon, gamma)IBA
11/2007
1AntigensIBA
11/2007
1ArtesunateIBA
11/2006
1Antimalarials (Antimalarial Agents)IBA
11/2006
1artenimol (dihydroartemisinin)IBA
11/2006

Therapy/Procedure

19Therapeutics
01/2022 - 08/2007
7Drug Therapy (Chemotherapy)
11/2018 - 11/2007
2Duration of Therapy
11/2018 - 06/2015
1Intramuscular Injections
01/2022
1Injections
10/2021
1Aftercare (After-Treatment)
10/2020
1Art Therapy
10/2016
1Drug Tapering
01/2012